question: when calculating difference in energy for chair flips, if one group is axial and one group is equatorial in both chair conformations, do you always take the difference between the two value

asked by @maddiez3 • about 1 year ago • Organic Chemistry • 5 pts

s to calculate delta g, making it always positive? thanks!

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Hey there! So I agree that when one group is equatorial and the other is axial it would make sense that you will always take the difference. But delta G being (-) or (+) will still depend on the substituents. I hope this helps!

answered by @leot1 • about 1 year ago