Would the following synthesis work?

asked by @elianas4 • over 1 year ago • Organic Chemistry • 5 pts

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2 answers

Hi there! First answer looks great. Good job! For the second item, that synthesis will not work because in the 3rd step it will oxidize the entire R group to a carboxylic acid and only have a COOH group coming directly off the benzene. It’s called side chain oxidation if you want to look it up. However using grignard with an epoxide will get us the 2 carbon chain we want and a primary alcohol that can be oxidized. I attached a possible synthesis for it. Hope that helpsenter image description here

answered by @reyn • over 1 year ago

thank you!

answered by @elianas4 • over 1 year ago