Is there ever a mechanism that only favors Sn1 reactions?

asked by @ekino1 • over 1 year ago • Organic Chemistry • 5 pts

I know that with a neutral nucleophile on a second or third leaving group you get a mixture of both Sn1 and E1. So does that mean you never have only an Sn1 reaction without also having E1?

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1 answer

Hey @ekino1!

SN1 and E1 often occur together because the nucleophile/base is weak, but we can control our conditions to favor either SN1 or E1. Adding heat to a reaction will favor elimination. Solvents also have an impact on what kind of reaction will take place.

Hope this helped!

answered by @jonathan • over 1 year ago