We are given 2 reagents and we have to predict what they will do, and we have to choose whether they are SN1, SN2, E1 or E2...

asked by @parkerh4 • over 1 year ago • Organic Chemistry • 5 pts

My problem is, the negative charges are not labeled, so I don't know when to use SN2 or E2. How can I determine this?

Add comment
1 answer

Hey, @parkerh4!

Reagents with a charge will often be provided with a counterion. For example, methoxide (MeO—) is often given as sodium methoxide (MeONa). We know that the sodium and oxygen have to be an ionic bond and that sodium has a positive charge, so the oxygen must have a negative charge.

The strength of the nucleophile/base is determined by the charge, and you can use that information to figure out what mechanism and product you will get by following the Big Daddy Flowchart, which you can find here:

https://www.clutchprep.com/organic-chemistry/big-daddy-mechanism-flowchart/?c_id=4470

answered by @jonathan • over 1 year ago