Concept #1: The Refractory Period(s)
Concept #2: The Refractory Period and Unidirectional Spread of APs
Practice: You have a big neuron siting in a dish. You stick an electrode into the middle of the axon and depolarize it. Identify each of the following as true or false. For each, why?
1) The AP spreads toward the axon terminal/synapse.
2) The AP spreads toward the cell body.
Practice: Amiodarone is a drug that blocks voltage-gated K+ channels. Assuming complete blockage of voltage-gated K+ channels, which of the following will be prolonged in a neuron treated with amiodarone?