Anatomy & Physiology Human Physiology: An Integrated Approach
Human Physiology: An Integrated Approach

Human Physiology: An Integrated Approach Silverthorn • 7th Edition • 9780321981226,

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Ch. 1 - Introduction to Physiology

Homeostasis and Feedback Control

Ch. 2 - Molecular Interactions

Fundamental Chemistry Chemical Reactions, Le Chatelier's Principle and Binding Equilibria Solutions and Solubility Proteins I: Protein Structure Proteins II: Ligand Binding and Regulation of Function

Ch. 3 - Compartmentation: Cells and Tissues

Cells to Organ Systems The Plasma Membrane Body Fluid Compartments Review of Physiologically-Relevant Organelles Epithelial Tissues Classifying Epithelial Tissues Simple Epithelial Tissues Pseudostratified Epithelial Tissues Stratified Epithelial Tissues Transitional Epithelial Tissues Exocrine Gland Classifications Connective Tissues Embryonic Connective Tissue Non-Embryonic Connective Tissue Proper Loose Connective Tissue Proper Dense Connective Tissue Supporting Connective Tissue Muscle Tissue Nervous Tissue Development and Modification of Tissue Membranes

Ch. 4 - Energy and Cellular Metabolism

Thermodynamics for Physiology: The Energetics of (Bio)Chemical Reactions Chemical Reactions, Le Chatelier's Principle and Binding Equilibria Enzymes and their Regulation Metabolism I: Overview Metabolism II: Glycolysis Metabolism III: Aerobic Metabolism Metabolism IV: Protein and Lipid Catabolism Metabolism V: Anabolism Protein Synthesis and Gene Expression

Ch. 5 - Membrane Dynamics

Osmosis: Osmolarity, Osmotic Pressure and Tonicity Diffusion Protein-Mediated Transport Vesicle-Based Transport: Endocytosis and Exocytosis Crossing an Epithelial Layer: The Trans- and Paracellular Pathway The Resting Membrane Potential I: Forces and Ohm's Law The Resting Membrane Potential II: Development of a Membrane Potential The Resting Membrane Potential III: The Nernst and Goldman-Hodgkin-Katz Equations

Ch. 6 - Communication, Integration, and Homeostasis

Cell-to-Cell Connections and Messages Signal Transduction I: General Ideas Signal Transduction II: G-Protein Coupled Receptors Signal Transduction III: Other Transduction Pathways Signal Transduction IV: Details of the Gs, Gi, and Gq Transduction Pathways

Ch. 7 - Introduction to the Endocrine System

Basics of Hormone Function Hormone Classification and Mechanism of Action The Hypothalamus and Pituitary Gland

Ch. 8 - Neurons: Cellular and Network Properties

Cells of the Nervous System Electrical Signals in Neurons I: Membrane Potential Vocabulary Electrical Signals in Neurons II: Graded vs. Action Potentials Electrical Signals in Neurons III: Action Potentials Action Potential Propagation The Refractory Period Neuronal Cell-to-Cell Communication: Synaptic Transmission Synaptic Integration I: Post-Synaptic Potentials (EPSPs and IPSPs) Synaptic Integration II: Summation Common Neurotransmitters and Receptors

Ch. 9 - The Central Nervous System

The Brain-- Anatomy and Function The Spinal Cord Cranial Nerves Spinal Nerves-- Dermatomes and Myotomes Spinal Tracts-- Introduction to Ascending and Descending Pathways

Ch. 10 - Sensory Physiology

General Principles of Sensation and Sensory Receptors The Somatic Senses Chemoreception I: Smell Chemoreception II: Taste The Ear: Hearing The Ear: Equilibrium The Eye and Vision

Ch. 11 - Efferent Division: Autonomic and Somatic Motor Control

Autonomic Nervous System: Divisions and Structure The Adrenal Glands

Ch. 12 - Muscles

Skeletal Muscle Cellular Anatomy-- Muscles to Sarcomeres Skeletal Muscle Contraction I: The Cellular Level Skeletal Muscle Contraction II: Tension and Length-Tension Curves Skeletal Muscle Contraction III: Summation and Tetanus Skeletal Muscle Contraction IV: Isotonic vs. Isometric Contractions Energy Requirements of Skeletal Muscle-- Fiber Types and Fatigue Smooth Muscle

Ch. 13 - Integrative Physiology I: Control of Body Movement

Neural Control of Skeletal Muscle--Skeletal Muscle Reflexes

Ch. 14 - Cardiovascular Physiology

Overview of the Cardiovascular System Blood Flow: Ohm's and Poiseuille's Laws Heart Anatomy Cardiac Muscle Excitation-Contraction Coupling Cardiac Muscle Action Potentials Cardiac Electrophysiology I: Nodal Fibers, Pacemaker Potentials, and Automaticity Cardiac Electrophysiology II: Electrical Conduction Pathways Electrocardiography I: Electrodes, Currents, and Leads Electrocardiography II: Interpreting an EKG The Cardiac Cycle I: Understanding the Valves The Cardiac Cycle II: Systole and Diastole The Cardiac Cycle III: Volumes in the Left Ventricle The Cardiac Cycle IV: Heart Sounds The Cardiac Cycle V: The Wiggers Diagram The Cardiac Cycle VI: The Ventricular Pressure-Volume Loop Cardiac Output I: Definitions Cardiac Output II: The Frank-Starling Law of the Heart Cardiac Output III: Autonomic Regulation of Cardiac Function

Ch. 15 - Blood Flow and the Control of Blood Pressure

Overview of the Cardiovascular System The Blood Vessels Blood Pressure: Definitions and Measurement Flow Around the Circulatory Loop Short-Term Regulation of Blood Pressure--the Baroreceptor Reflexes Hormonal Regulation of Blood Pressure I: Vasopressin/Anti-Diuretic Hormone Hormonal Regulation of Blood Pressure II: The Renin-Angiotensin-Aldosterone System Capillary Exchange I: Diffusion Capillary Exchange II: Bulk Flow and the Starling Equation of Ultrafiltration

Ch. 16 - Blood

Blood Hemostasis-- The Clotting Cascade

Ch. 17 - Mechanics of Breathing

Anatomy and Organization of the Respiratory System Measuring Pressure of a Mixture of Gases-- Partial Pressures and Dalton's Law Ventilation I: Boyle's Law Ventilation II: Mechanics of Inspiration and Expiration Properties of the Lungs-- Compliance, Elasticity, Resistance, and Surface Tension Lung Spirometry: Lung Volumes and Capacities Total vs. Alveolar Ventilation and the Anatomic Dead Space

Ch. 18 - Gas Exchange and Transport

Gas Exchange I: Diffusion in the Alveoli Gas Exchange II: Ventilation and Perfusion and V/Q Ratios Gas Transport in the Blood I: Oxygen and Hemoglobin Binding Gas Transport in the Blood II: Carbon Dioxide Regulation of Ventilation I: Neural Control of Respiratory Muscles Regulation of Ventilation II: Chemoreceptors and Effects of CO2, pH, O2

Ch. 19 - The Kidneys

Anatomy of the Urinary System Basic Renal Processes The Glomerulus Reabsorption I: General Concepts of Reabsorption in the Kidney Reabsorption II: Reabsorption (and Secretion) in the Proximal Tubule Reabsorption III: The Loop of Henle Reabsorption IV: The Distal Tubule Reabsorption V: The Collecting Duct and Effects of ADH and Aldosterone Clearance-- Measuring Glomerular Filtration Rate and Renal Plasma Flow

Ch. 20 - Integrative Physiology II: Fluid and Electrolyte Balance

Body Fluid Compartments Hormonal Regulation of Blood Pressure I: Vasopressin/Anti-Diuretic Hormone Hormonal Regulation of Blood Pressure II: The Renin-Angiotensin-Aldosterone System Disturbing Blood pH-- Sources of Acid and Base and Acidosis vs. Alkalosis Calculating Blood pH-- The Henderson-Hasselbalch Equation Causes of pH Disturbances-- Metabolic vs. Respiratory Acidosis and Alkalosis Controlling Blood pH I: Respiratory Compensation Controlling Blood pH II: Renal Compensation in the Proximal Tubule and Collecting Duct

Ch. 21 - The Digestive System

Anatomy and Function of the Digestive System The Macronutrients: Carbohydrates, Lipids, and Proteins From Mouth to Stomach The Stomach The Digestive Accessory Organs I: The Liver and Gall Bladder The Digestive Accessory Organs II: The Exocrine Pancreas The Small Intestine I : Arrival at the Duodenum and Initiation of Pancreas/Gall Bladder Secretion The Small Intestine II: Digestion and Absorption of the Three Macronutrients The Small Intestine III: Motility The Large Intestine Regulation of Gastrointestinal Function

Ch. 22 - Metabolism and Energy Balance

Review of Metabolism-- Catabolic and Anabolic Processes Measuring Metabolism-- Basal Metabolic Rate and Respiratory Quotient Fed-State Metabolism and the Effects of Insulin Fasted-State Metabolism and the Effects of Glucagon Type I and Type II Diabetes Mellitus Body Temperature Regulation

Ch. 23 - Endocrine Control of Growth and Metabolism

The Adrenal Glands The Thyroid Gland The Parathyroid Gland Calcium (and Phosphate) Regulation I-- Bone Growth and Remodeling Calcium (and Phosphate) Regulation II-- Parathyroid Hormone, Vitamin D, and Calcitonin

Ch. 24 - The Immune System

Pathogens of the Human Body Anatomy of the Immune "System" Cells of the Immune System Innate Immunity Acquired Immunity I: Introduction to Lymphocytes Acquired Immunity II: B Lymphocytes and Antibodies Acquired Immunity III: The Major Histocompatibility Complex and Antigen Presentation Acquired Immunity IV: T Lymphocytes and Cell-Mediated Responses

Ch. 26 - Reproduction and Development

Review of Mitosis and Meiosis Male Reproduction I: Anatomy of the Male Reproductive System Male Reproduction II: Spermatogenesis and Spermiogenesis Female Reproduction I: Anatomy of the Female Reproductive System Female Reproduction II: Oogenesis and Folliculogenesis Female Reproduction III: The Menstrual Cycle Sex Determination and Differentiation-- Boy or Girl? Making Babies I: The Sexual Response and Sexual Intercourse Making Babies II: Fertilization Making Babies III: Early Development and Implantation Making Babies IV: Labor and Delivery (Parturition) Making Babies V: Lactation-- Feeding the Baby

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