Innate Immunity

Concept: Physical Barriers

3m

Concept: Identification of Foreign Invaders by the Innate Immune System-- PAMPs and PRRs

4m

Concept: Molecular and Cellular Defenses of the Innate Immune System

6m

Problem: A protein called C3b is a part of the complement family. It functions in innate immunity by adhering to the surface of pathogens; pathogens coated by C3b are much more likely to be phagocytosed by phagocytes that engulf and kill the pathogen. Which of the following accurately describes the protein C3b?

2m

Problem: A protein called C3b is a part of the complement family. It functions in innate immunity by adhering to the surface of pathogens; pathogens coated by C3b are much more likely to be phagocytosed by phagocytes that engulf and kill the pathogen. Which of the following cells are most likely to interact with C3b-coated pathogens? (Choose all that apply.)

1m

Problem: Paroxysmal nocturnal hemoglobinuria (PNH) is an auto-immune disease in which the immune system attacks and destroys red blood cells (RBCs). In PNH, RBCs die by lysis; that is, some part of the immune system creates holes in the RBC cell membranes, causing them to fill with water and burst. Which part of the immune system is likely dysfunctional in PNH and causes this inappropriate lysis of RBCs?

3m