Ch. 17 - Cardiovascular Physiology I: The HeartWorksheetSee all chapters
All Chapters
Ch. 1 - Introduction to Physiology
Ch. 2 - Molecules and Molecular Interactions
Ch. 3 - Cells and Tissues
Ch. 4 - Cell Metabolism: Bioenergetics, Enzymes, and Respiration
Ch. 5 - Membrane Dynamics
Ch. 6 - Cell Communication
Ch. 7 - Integumentary System
Ch. 8 - Bone and Cartilage
Ch. 9 - Skeletal System
Ch. 10 - Joints
Ch. 11 - Muscles
Ch. 12 - The Nervous System I: Neurons and Neuronal Networks
Ch. 13 - The Nervous System II: The Central Nervous System
Ch. 14 - The Autonomic Nervous System
Ch. 15 - Sensory Physiology
Ch. 16 - The Endocrine System
Ch. 17 - Cardiovascular Physiology I: The Heart
Ch. 18 - Cardiovascular Physiology II: Blood, Blood Vessels, Circulation, and Exchange
Ch. 19 - The Urinary System
Ch. 20 - Respiratory Physiology
Ch. 21 - Acid-Base Balance-- Controlling Blood pH
Ch. 22 - Introduction to the Immune System
Ch. 23 The Lymphatic System
Ch. 23 - The Digestive System
Ch. 24 - Regulation of Metabolism and Energy Balance
Ch. 25 - Human Sexual Reproduction and Development

Concept #1: Cardiac Muscle Excitation-Contraction Coupling

Practice: Epinephrine is a hormone (and drug) that binds to β1 adrenergic receptors on cardiac contractile cells. Binding of epinephrine to β1 receptors activates an intracellular signaling cascade that increases the Ca2+ conductance of both L-type Ca2+ channels (LTCCs) and ryanodine receptors (RyRs). Which of the following is the likely effect of epinephrine on the contraction force generated by cardiac contractile cells?

Practice: Epinephrine is a hormone (and drug) that binds to β1 adrenergic receptors on cardiac contractile cells. Binding of epinephrine to β1 receptors activates an intracellular signaling cascade that increases the activity of the sarcoplasmic reticulum/endoplasmic reticulum Ca2+ ATPase (SERCA). Which of the following is the likely effect of epinephrine on the contraction duration of cardiac contractile cells?

Practice: Digoxin is a drug that (indirectly) inhibits the activity of the Na+/Ca2+ Exchanger (NCX) in the membranes of cardiac contractile cells. Which of the following is the likely effect of digoxin on the contraction force generated by cardiac contractile cells?