The E1 Mechanism

The E1 mechanism is similar to E2 in that you get an elimination product, but the path to get there is completely different. It’s important that we understand how it’s different from E2. 

Summary: A neutral nucleophile reacts with an inaccessible leaving group to produce elimination in two-step.

Properties of E1 reactions:

  • Nucleophile =  Weak
  • Leaving Group =  Highly Substituted
  • Reaction coordinate = Intermediate
  • Reaction = Two-Step
  • Rate =  Unimolecular
  • Rate =  k[RX]
  • Stereochemistry = Non-stereospecific

Problem: Predict the product

6m

Problem: Predict the product

6m