Time to start learning about some of the most important reactions in all of organic chemistry. In fact, you’re never allowed to forget this one!
Concept #1: Drawing the SN2 Mechanism
Summary: A negatively charged nucleophile reacts with an accessible leaving group to produce substitution in one-step.
Concept #2: Understanding the properties of SN2.
Properties of SN2 reactions:
Rank the following alkyl halides in order of reactivity toward SN2 reaction.
Example #1: Rank the following alkyl halides in order of reactivity toward SN2 reaction.
Practice: Predict the product of the following reaction.
The product must contain inversion of configuration if the original leaving group is located on a chiral center.
Practice: Predict the product of the following reaction: