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Nucleophilic Aromatic Substitution Solutions Library

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30 solutions

Nucleophilic Aromatic Substitution

Q. Draw the major organic product formed with para-bromonitrobenzene reacts with sodium ethoxide under heated conditions. 

Solved • Jul 23, 2018

Nucleophilic Aromatic Substitution

Q. Two major organic products are formed in the reaction of p-chlorotoluene with sodium amide. Draw the structure of both products.

Solved • Jun 8, 2018

Nucleophilic Aromatic Substitution

Q. Draw the structure of the organic product formed from the reaction of sodium methoxide with 1-chloro-4-nitrobenzene. Be sure to show formal charges.

Solved • Jun 4, 2018

Nucleophilic Aromatic Substitution

Q. Draw the anionic intermediate in of a nucleophilic aromatic substitution (addition-elimination) involving the following reaction.4-chloropyridine a...

Solved • Dec 21, 2017

Nucleophilic Aromatic Substitution

Q. Draw the anionic intermediate in of a nucleophilic aromatic substitution (addition-elimination) involving the following reaction.Chlorobenzene and KOH

Solved • Dec 21, 2017

Nucleophilic Aromatic Substitution

Q. Which of the following would most readily undergo a nucleophilic aromatic substitution (via the addition-elimination pathway)?

Solved • Dec 21, 2017

Nucleophilic Aromatic Substitution

Q. Which one of the following compounds would most readily undergo nucleophilic aromatic substitution with Na+ -OCH3 via the addition-elimination path...

Solved • Dec 20, 2017

Nucleophilic Aromatic Substitution

Q. Draw an example of a Meisenheimer Complex that is capable of forming at room temperature

Solved • Dec 20, 2017

Nucleophilic Aromatic Substitution

Q. Show the anionic intermediate in a nucleophilic aromatic substitution reaction involving the following pyrimidine derivative and sodium methoxide.

Solved • Dec 20, 2017

Nucleophilic Aromatic Substitution

Q. Provide the mechanism that occurs when a nucleophile Nu- reacts with 2-chloropyridine in an addition-elimination pathway

Solved • Dec 20, 2017

Nucleophilic Aromatic Substitution

Q. Which one of the following would most readily undergo nucleophilic aromatic substitution with sodium methoxide?

Solved • Dec 20, 2017

Nucleophilic Aromatic Substitution

Q. Which one of the following would most readily undergo nucleophilic aromatic substitution via the addition-elimination pathway?

Solved • Dec 20, 2017

Nucleophilic Aromatic Substitution

Q. Provide a detailed, stepwise mechanism for the following reaction.

Solved • Jul 22, 2017

Nucleophilic Aromatic Substitution

Q. Rank the following compounds in descending order of reactivity toward hydroxide ion with the most reactive first and the least reactive last.

Solved • Jun 5, 2017

Nucleophilic Aromatic Substitution

Q.  Predict the product(s) for the following reaction. When appropriate, Iabel major and minor.

Solved • Mar 6, 2017

Nucleophilic Aromatic Substitution

Q. Which of the following is not true about Meissenheimer complexes? a. They are resonance-stabilized anions b. They are formed upon addition of a n...

Solved • Dec 21, 2016

Nucleophilic Aromatic Substitution

Q. Which of the following compounds is least reactive in the nucleophilic aromatic substitution reaction with NaOH? a. 2,4-dinitrochlorobenzene b. p-...

Solved • Oct 4, 2016

Nucleophilic Aromatic Substitution

Q. Predict the major product for the following reaction paying attention to the regio- and stereochemistry.

Solved • Sep 27, 2016

Nucleophilic Aromatic Substitution

Q. Predict the major product for the following reaction paying attention to the regio- and stereochemistry.  

Solved • Sep 27, 2016

Nucleophilic Aromatic Substitution

Q. What is the expected product of this reaction?

Solved • May 8, 2016

Nucleophilic Aromatic Substitution

Q. Which aryl chloride reacts the fastest with NaOH?

Solved • May 8, 2016

Nucleophilic Aromatic Substitution

Q. Which description is most applicable to the mechanism of this reaction?

Solved • May 8, 2016

Nucleophilic Aromatic Substitution

Q. Place the following molecules in order of their reactivity with CH3S– Na+ via an SnAr mechanism. Label the most reactive as #1 and the least reacti...

Solved • May 6, 2016

Nucleophilic Aromatic Substitution

Q. Draw the organic product(s) for the following reaction. Indicate stereochemistry where appropriate. Assume an aqueous workup, when necessary. A rea...

Solved • May 4, 2016

Nucleophilic Aromatic Substitution

Q. Draw a reasonable mechanism for the reaction below. 

Solved • May 4, 2016

Nucleophilic Aromatic Substitution

Q. What is the product when compound T reacts with sodium methoxide in methanol at high temperatures?  

Solved • Mar 9, 2016

Nucleophilic Aromatic Substitution

Q. Predict the principal organic product of the following reaction.

Solved • Feb 29, 2016

Nucleophilic Aromatic Substitution

Q. Predict the principal organic product of the following reaction.

Solved • Feb 29, 2016

Nucleophilic Aromatic Substitution

Q. Draw the structural formula of the major organic product in the box below.  

Solved • Feb 11, 2016

Nucleophilic Aromatic Substitution

Q. Predict the major product for each of the following reactions paying attention to the regio- and stereochemistry. If there is no reaction, write ju...

Solved • Feb 1, 2016