Problem: An amino acid backbone is given below. Add the side chain to show proline at physiological pH.Note: If you need to start over, select the double red arrows button.

🤓 Based on our data, we think this question is relevant for Professor Kimbrough's class at CU.

FREE Expert Solution

Recall that if pH > pKa, the group will be deprotonated and 

if pH < pKa, group gets protonated

For proline, pKa of -COOH is 1.99 while -NH2 is 10.60

View Complete Written Solution
Problem Details

An amino acid backbone is given below. Add the side chain to show proline at physiological pH.

Note: If you need to start over, select the double red arrows button.

Frequently Asked Questions

What scientific concept do you need to know in order to solve this problem?

Our tutors have indicated that to solve this problem you will need to apply the Acid-Base Properties of Amino Acids concept. You can view video lessons to learn Acid-Base Properties of Amino Acids . Or if you need more Acid-Base Properties of Amino Acids practice, you can also practice Acid-Base Properties of Amino Acids practice problems.

What professor is this problem relevant for?

Based on our data, we think this problem is relevant for Professor Kimbrough's class at CU.