Recall that if pH > pKa, the group will be deprotonated and
if pH < pKa, group gets protonated
For proline, pKa of -COOH is 1.99 while -NH2 is 10.60
An amino acid backbone is given below. Add the side chain to show proline at physiological pH.
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What scientific concept do you need to know in order to solve this problem?
Our tutors have indicated that to solve this problem you will need to apply the Acid-Base Properties of Amino Acids concept. You can view video lessons to learn Acid-Base Properties of Amino Acids . Or if you need more Acid-Base Properties of Amino Acids practice, you can also practice Acid-Base Properties of Amino Acids practice problems.
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