Problem: An amino acid backbone is drawn below. Draw the histidine side chain structure for the predominant ionization state of histidine at pH 8.0.Note: If you need to start over, select the double red arrows button. 

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FREE Expert Solution

Recall that if pH > pKa, the group will be deprotonated and 

if pH < pKa, group gets protonated

For histidine, pKa of -COOH is 1.82 while -NH2 is 9.17

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Problem Details

An amino acid backbone is drawn below. Draw the histidine side chain structure for the predominant ionization state of histidine at pH 8.0.

Note: If you need to start over, select the double red arrows button.