Problem: An amino acid backbone is drawn below. Draw the histidine side chain structure for the predominant ionization state of histidine at pH 8.0.Note: If you need to start over, select the double red arrows button.
FREE Expert Solution
Recall that if pH > pKa, the group will be deprotonated and
if pH < pKa, group gets protonated
For histidine, pKa of -COOH is 1.82 while -NH2 is 9.17
Problem Details
An amino acid backbone is drawn below. Draw the histidine side chain structure for the predominant ionization state of histidine at pH 8.0.
Note: If you need to start over, select the double red arrows button.
Frequently Asked Questions
What scientific concept do you need to know in order to solve this problem?
Our tutors have indicated that to solve this problem you will need to apply the Acid-Base Properties of Amino Acids concept. You can view video lessons to learn Acid-Base Properties of Amino Acids . Or if you need more Acid-Base Properties of Amino Acids practice, you can also practice Acid-Base Properties of Amino Acids practice problems.
What professor is this problem relevant for?
Based on our data, we think this problem is relevant for Professor Ravi's class at LEHMAN-CUNY.