Problem: What Grignard reagent and carbonyl compound can be used to prepare the antidepressant venlafaxine (trade name Effexor)?

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What Grignard reagent and carbonyl compound can be used to prepare the antidepressant venlafaxine (trade name Effexor)?

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What scientific concept do you need to know in order to solve this problem?

Our tutors have indicated that to solve this problem you will need to apply the Organometallic Retrosynthesis concept. If you need more Organometallic Retrosynthesis practice, you can also practice Organometallic Retrosynthesis practice problems.

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Based on our data, we think this problem is relevant for Professor Gould's class at ASU.