Organic Chemistry Practice Problems Amine Alkylation Practice Problems Solution: Answer the following questions about the Alkylatio...

Solution: Answer the following questions about the Alkylation of Amines by circling T (True) or F (False).   1. The lone pair of electrons on a primary amine cannot react in a nucleophilic manner. T or F 2. The substitution of the alkyl halide used in polyalkylation will have an effect on the yield of the product. T or F 3. With excess base and alkyl halide a polyalkylation does not result in polyalkylated amines. T or F 4. One way to prevent over alkylation is to run the reaction with excess amine. T or F

Problem

Answer the following questions about the Alkylation of Amines by circling T (True) or F (False).

 

1. The lone pair of electrons on a primary amine cannot react in a nucleophilic manner. T or F

2. The substitution of the alkyl halide used in polyalkylation will have an effect on the yield of the product. T or F

3. With excess base and alkyl halide a polyalkylation does not result in polyalkylated amines. T or F

4. One way to prevent over alkylation is to run the reaction with excess amine. T or F