Problem: What set of reaction conditions would favor an SN1 reaction on 2-bromo-3-methylbutane? a)Strong nucleophile in a protic solvent. b) Strong nucleophile in an aprotic solvent. c) Weak nucleophile in a protic solvent. d) Weak nucleophile in an aprotic solvent.

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Problem Details

What set of reaction conditions would favor an SN1 reaction on 2-bromo-3-methylbutane?

a)Strong nucleophile in a protic solvent.

b) Strong nucleophile in an aprotic solvent.

c) Weak nucleophile in a protic solvent.

d) Weak nucleophile in an aprotic solvent.

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Based on our data, we think this problem is relevant for Professor Benson's class at KU.