Problem: Focusing on just one of the six membered rings from the structure in  avermectin, draw this portion as a cyclohexane chair below. Perform a  chair flip, and circle the more stable conformation. Provide a one sentence rationale for which conformation you circled.

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Focusing on just one of the six membered rings from the structure in  avermectin, draw this portion as a cyclohexane chair below. Perform a  chair flip, and circle the more stable conformation. Provide a one sentence rationale for which conformation you circled.

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Based on our data, we think this problem is relevant for Professor Warncke's class at EMORY.