Problem: Propose a sequence of reactions to prepare the target compound from the indicated starting materials. All of the carbon atoms present in the target compound must originate in the designated starting materials! You may use as much of each starting material as necessary to achieve the desired synthesis. In addition to these staring materials, you may also use any other organic and/or inorganic reagents necessary. It is OK to use other reagents that contain carbon, as long as these carbon atoms do not end up in the final target compound! It is only necessary to show the overall transformations involved in your proposed syntheses – please do not write curved arrow mechanisms in answering this question! Be sure that your final answer is indicated clearly and unambiguously.

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Propose a sequence of reactions to prepare the target compound from the indicated starting materials. All of the carbon atoms present in the target compound must originate in the designated starting materials! You may use as much of each starting material as necessary to achieve the desired synthesis. In addition to these staring materials, you may also use any other organic and/or inorganic reagents necessary. It is OK to use other reagents that contain carbon, as long as these carbon atoms do not end up in the final target compound! It is only necessary to show the overall transformations involved in your proposed syntheses – please do not write curved arrow mechanisms in answering this question! Be sure that your final answer is indicated clearly and unambiguously.

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Our tutors have indicated that to solve this problem you will need to apply the Addition Retrosynthesis concept. If you need more Addition Retrosynthesis practice, you can also practice Addition Retrosynthesis practice problems.

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