Problem: Draw the structures of organic compounds A and B. Indicate stereochemistry where applicable.

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We will use a cleaner bond-line structure for the synthesis.


NaNHproduces an alkynide which can then attack the alkyl halide (RX) which results in the addition of the R group to the alkyne. 


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Draw the structures of organic compounds A and B. Indicate stereochemistry where applicable.


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Our tutors have indicated that to solve this problem you will need to apply the Alkynide Retrosynthesis concept. If you need more Alkynide Retrosynthesis practice, you can also practice Alkynide Retrosynthesis practice problems.