Multistep synthesis of benzocaine involves:
For Multi-Step Synthesis of Benzocaine:
1) Why don't we simply oxidize p-toluidine with KMnO4 to make p-aminobenzoic acid? Wouldn't that be a faster method? What unwanted reaction(s) may occur?
2)The isolation of p-aminobenzoic acid is the trickiest step due to the formation of an amino compound. Why don't we do the esterification step prior to the deprotection step?
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Based on our data, we think this problem is relevant for Professor Mead's class at SEMINOLESTATE.