Problem: Shown below is the conversion at pivaldehyde to tert - butyl benzoate Fill in the best reagents to achieve this synthetic transformation. mCPBANaBH4KOBuBnMgBrBenzaldehydePhMgBrPCC/DCMH2O

FREE Expert Solution

The multistep synthesis for this transformation will appear as:

1-2. Grignard reaction (nucleophilic addition)

3. Mild oxidation (alcohol to ketone)

View Complete Written Solution
Problem Details

Shown below is the conversion at pivaldehyde to tert - butyl benzoate Fill in the best reagents to achieve this synthetic transformation. 

mCPBA

NaBH4

KOBu

BnMgBr

Benzaldehyde

PhMgBr

PCC/DCM

H2O

Frequently Asked Questions

What scientific concept do you need to know in order to solve this problem?

Our tutors have indicated that to solve this problem you will need to apply the Carbonyl Retrosynthesis concept. If you need more Carbonyl Retrosynthesis practice, you can also practice Carbonyl Retrosynthesis practice problems.