Problem: Provide an appropriate alkyne starting material A and intermediate product beta. Omit byproducts. The number of carbon atoms in the starting material should be the same as in the final product.
FREE Expert Solution
Hydroboration-Oxidation
- Step 1: Alkyne + R2BH/THF → syn addition (anti-Markovnikov)
- regioselective Hydroboration
- Step 2: Alkene—BR2 + H2O2 /NaOH/ H2O → enol → enol-keto tautomerization → carbonyl (C=O) product
Problem Details
Provide an appropriate alkyne starting material A and intermediate product beta. Omit byproducts. The number of carbon atoms in the starting material should be the same as in the final product.
