Problem: For the synthetic sequence below, choose the correct reagent for each reaction.Rxn 1a) H+, H2Ob) RCO3Hc) t-BuO-d) HBrRxn 2a)  RCO3Hb) -OHc) H2SO4d) 1.CH3Li, 2.H+Rxn 3a) H+, H2Ob) 1.CH3CH2MgBr, 2.H+c) -OHd) 1.CH3Li, 2.H+

FREE Expert Solution

1st reaction:

1° alkyl halide → alkene → E2 mechanism

E2 mechanism → t-BuO- as base


2nd reaction:

alkene → epoxide → epoxidation

epoxidation → RCO3

View Complete Written Solution
Problem Details

For the synthetic sequence below, choose the correct reagent for each reaction.

Rxn 1

a) H+, H2O

b) RCO3H

c) t-BuO-

d) HBr


Rxn 2

a)  RCO3H

b) -OH

c) H2SO4

d) 1.CH3Li, 2.H+


Rxn 3

a) H+, H2O

b) 1.CH3CH2MgBr, 2.H+

c) -OH

d) 1.CH3Li, 2.H+

Frequently Asked Questions

What scientific concept do you need to know in order to solve this problem?

Our tutors have indicated that to solve this problem you will need to apply the Organometallic Retrosynthesis concept. If you need more Organometallic Retrosynthesis practice, you can also practice Organometallic Retrosynthesis practice problems.