alkene → alcohol to the least substituted side (anti-Markovnikov addition) → Hydroboration oxidation
This follows a mechanism:
(1) Electrophilic addition
What reagents can best be used to accomplish the following transformation?
A) 1. BH3-THF 2. HO-, H2O2
B) H+, H2O
C) 1. Hg(OAc)2, H2O/THF 2. NaBH4
D) 1. Hg(O2CCF3)2, CH3OH 2. NaBH4
E) NaOH, H2O
Frequently Asked Questions
What scientific concept do you need to know in order to solve this problem?
Our tutors have indicated that to solve this problem you will need to apply the Addition Retrosynthesis concept. If you need more Addition Retrosynthesis practice, you can also practice Addition Retrosynthesis practice problems.
What professor is this problem relevant for?
Based on our data, we think this problem is relevant for Professor Meier's class at UK.