Problem: Consider the directing effects of the substituents on salicylamide and predict the possible structures of the iodination products. Which do you think will be the major product? Explain your reasoning. 

FREE Expert Solution

Inspecting the substituents attached:

  • Since C=O group is deactivating, the -OH group will direct the EAS  reactions
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Problem Details

Consider the directing effects of the substituents on salicylamide and predict the possible structures of the iodination products. Which do you think will be the major product? Explain your reasoning. 

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What scientific concept do you need to know in order to solve this problem?

Our tutors have indicated that to solve this problem you will need to apply the EAS: Ortho vs. Para Positions concept. You can view video lessons to learn EAS: Ortho vs. Para Positions. Or if you need more EAS: Ortho vs. Para Positions practice, you can also practice EAS: Ortho vs. Para Positions practice problems.