EAS: Retrosynthesis Video Lessons

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Problem: Complete the synthesis below by selecting or drawing the reagents.Reagent A:a) Br2, FeBr3b) Mg, THFc) Mg, Br2Reagent B:a) Mg, THFb) HBrc) Br2, FeBr3Reagent C:a) PCCb) H3O+c) KMnO4

FREE Expert Solution

Reaction 1

  • Benzene needs to be activated.
  • Then it needs to be transformed into a Grignard reagent

Reaction 2

  • Needs to add carbons and OH group

Reaction 3

  • oxidize OH to aldehyde

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Problem Details

Complete the synthesis below by selecting or drawing the reagents.

Reagent A:

a) Br2, FeBr3

b) Mg, THF

c) Mg, Br2

Reagent B:

a) Mg, THF

b) HBr

c) Br2, FeBr3

Reagent C:

a) PCC

b) H3O+

c) KMnO4

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Based on our data, we think this problem is relevant for Professor Mallari's class at CSUSB.