We are asked to highlight the groups that will sterically interact with the methyl group in a 1,3-diaxial fashion.
Diaxial interaction (1,3-diaxial interaction) is an interaction between two axial substituents on a cyclohexane ring.
• axial groups = ↑ energy or ↓ stability
• equatorial groups = ↓ energy or ↑ stability
1,3 means that position 1 (Carbon 1 on the ring) is our target group (methyl, CH3) and the other axial group would be on position 3 (carbon 3 on the ring).
For the substituted cyclohexane compound given below, highlight the groups - by clicking on atoms - that will sterically interact with the methyl group in a 1,3-diaxial fashion.