Ch. 22 - Condensation ChemistryWorksheetSee all chapters
All Chapters
Ch. 1 - A Review of General Chemistry
Ch. 2 - Molecular Representations
Ch. 3 - Acids and Bases
Ch. 4 - Alkanes and Cycloalkanes
Ch. 5 - Chirality
Ch. 6 - Thermodynamics and Kinetics
Ch. 7 - Substitution Reactions
Ch. 8 - Elimination Reactions
Ch. 9 - Alkenes and Alkynes
Ch. 10 - Addition Reactions
Ch. 11 - Radical Reactions
Ch. 12 - Alcohols, Ethers, Epoxides and Thiols
Ch. 13 - Alcohols and Carbonyl Compounds
Ch. 14 - Synthetic Techniques
Ch. 15 - Analytical Techniques: IR, NMR, Mass Spect
Ch. 16 - Conjugated Systems
Ch. 17 - Aromaticity
Ch. 18 - Reactions of Aromatics: EAS and Beyond
Ch. 19 - Aldehydes and Ketones: Nucleophilic Addition
Ch. 20 - Carboxylic Acid Derivatives: NAS
Ch. 21 - Enolate Chemistry: Reactions at the Alpha-Carbon
Ch. 22 - Condensation Chemistry
Ch. 23 - Amines
Ch. 24 - Carbohydrates
Ch. 25 - Phenols
Ch. 26 - Amino Acids, Peptides, and Proteins

Solution: The first two steps in the base-catalyzed condensation of acetaldehyde would be described as  A) attack of  –OH on the carbonyl carbon atom, then loss of water.  B) attack of  –OH on the carbonyl carbon atom, then the resultant anion attacks the carbonyl atom on a second molecule of acetaldehyde. C) –OH abstracts an α-hydrogen, then the resultant anion attacks the carbonyl carbon atom on a second molecule acetaldehyde. D) –OH abstracts the hydrogen atom from the carbonyl atom, then the resultant anion attacks the carbonyl carbon atom on a second molecule of acetaldehyde. 

Problem

The first two steps in the base-catalyzed condensation of acetaldehyde would be described as 

A) attack of  OH on the carbonyl carbon atom, then loss of water. 

B) attack of  OH on the carbonyl carbon atom, then the resultant anion attacks the carbonyl atom on a second molecule of acetaldehyde.

C) OH abstracts an α-hydrogen, then the resultant anion attacks the carbonyl carbon atom on a second molecule acetaldehyde.

D) OH abstracts the hydrogen atom from the carbonyl atom, then the resultant anion attacks the carbonyl carbon atom on a second molecule of acetaldehyde.