What is the Relationship Between Isomers?

One of the most frequently asked exam questions in this chapter is: “What is the relationship between the following two molecules?”. We’re going to learn a systematic method to solve these questions.  

Solving for R and S on every single molecule can be a headache. If the molecule hasn’t been rotated, feel free to use “different or same” as a surrogate for R and S (we’ll practice this so you see what I mean). 

Example: Identify the following compounds as identical, constitutional isomers, enantiomers or diastereomers

1m

Example: Identify the following compounds as identical, constitutional isomers, enantiomers or diastereomers.

2m

Example: Identify the following compounds as identical, constitutional isomers, enantiomers or diastereomers.

2m

Example: Identify the following compounds as identical, constitutional isomers, enantiomers or diastereomers.

3m