Test 2: Stereocenter Test

The gold standard chirality test for almost all molecules involves finding stereocenters.

Defining Stereocenters

Any atom that creates a stereoisomer after swapping two groups is called a stereocenter.

Types of Stereocenters

Example: Does the following molecule contain a stereogenic center? Is it chiral?

2m

Example: Does the following molecule contain a stereogenic center? Is it chiral?

3m

Example: Does the following molecule contain a stereogenic center? Is it chiral?

1m

Example: Does the following molecule contain a stereogenic center? Is it chiral?

3m

Example: Does the following molecule contain a stereogenic center? Is it chiral?

 

4m

Example: Does the following molecule contain a stereogenic center? Is it chiral?

3m