Example: Predict the MAJOR product of the following multistep transformation.4m
Example: Predict the MAJOR product of the following multistep transformation.6m
Example: Some hints on how to solve the transformation below2m
Example: Using the hints given, provide the reagents to best perform the following transformation.5m
Example: Using the hints given, provide the reagents to best perform the following transformation.3m
The fragrance of (Z)-1-phenylhex-2-en-1-ol resembles that of roses, with a delicate citrus edge. Show how you would synthesize this compound from benzaldehyde (PhCHO) and any other reagents you need.
Show how you would convert (a) oct-3-yne to cis-oct-3-ene (b) pent-2-yne to trans-pent-2-ene (c) cis-cyclodecene to trans-cyclodecene (d) but-1-yne to cis-hex-3-ene
Show how you would synthesize 2-phenylhex-3-yn-2-ol, starting with acetophenone (PhCOCH3) and any other reagents you need. (“2-ol” means there is an OH group on C2.)
Show how you would synthesize each compound, beginning with acetylene and any necessary additional reagents.
Show the reagents and intermediates involved in the other order of synthesis of dec-3-yne, by adding the ethyl group first and the hexyl group last.
Draw the structures of organic compounds A and B. Indicate stereochemistry where applicable.
In each reaction box, place the best reagent and conditions from the list below
2 equiv NaNH2, CH3Br, H2O, H2SO4, HgSO4, excess NaNH2, Na, NH3 (l),
H2O2, NaOH, H2O, NaBH4, HBr, CH3CH2Br, Br2, PBr3, H2, Lindlar catalyst BH3/THF
Predict the organic product(s) for the following reaction. Be sure to indicate stereochemistry when appropriate. If stereoisomers are produced draw one and label the relationship between the stereoisomers. (enantiomers, diastereomers, etc.).
Outline the following synthesis and list the reaction in the correct (forward order). (Hint: a retrosynthetic analysis can be very useful)
Predict the organic product(s) of the following reaction. When appropriate, be sure to indicate stereochemistry. If more than one product is formed be sure to indicate the major product, if stereoisomers are produced in the reaction be sure to indicate the relationship between them. Draw the answer in skeletal form.
Provide the products for each of the following synthesis. Your products must show stereo- and regiochemistry when necessary; label any chiral carbons with an asterisk.
An acetylide ion can also add to carbonyl compounds. Show the product of the following alkyne synthesis by providing the product in it's condensed structural formula and also showing the mechanism.
Show how you would perform the following transformation.
Fill in the box with the appropriate reactant, reagent, or product. Some boxes require more than one step.
Fill in the missing intermediate, reagent and product for the following synthesis.
Consider the strucutres below and answer the following questions.
j. Which compound could be prepared from 1-butyne by reaction with LDA/C 2H5I, followed by reaction with sodium in liqiud ammonia in the presense of a proton donor such as ethanol?
Provide the reagents required for the following transformations. Note, that some of these methods will require more than one chemical step. All the steps and reagents must be included.
What is the major product of this reaction sequence?
Alkene derivatives of pristine (2,6,10,14-tetramethylpentadecane) can be isolated from marine zooplankton and are important in the study of the marine food chain. Which of these routes is best for the preparation of pristane?
Predict the product for the following reaction:
Predict the final product(s) for the following multi-step reaction:
What is the IUPAC name for the expected final product of the transformation below?
Predict the products.
Predict the products
Predict the product.
What is the major organic product obtained from the following reaction?
What is the expected major final product of the reaction sequence shown below?
Determine the mechanism and predict the product of the reaction:
Predict the product of the reaction: