Alcohols are highly reactive. This can be a problem if we want to react on some other part of the molecule. How can we guarantee that a reaction won’t take place at the alcohol?
Concept #1: General features of Alcohol Protecting Groups.
For example, the following substitution reaction has a major problem as drawn. Can you spot the issue?
Protecting groups are reversible reactions that temporarily block groups from reacting, so that we can transform other parts of the molecule.