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Ch. 24 - Principles of DiseaseWorksheetSee all chapters
All Chapters
Ch. 1 - Introduction to Microbiology
Ch. 2 - Disproving Spontaneous Generation
Ch. 3 - Chemical Principles of Microbiology
Ch. 4 - Water
Ch. 5 - Molecules of Microbiology
Ch. 6 - Cell Membrane & Transport
Ch. 7 - Prokaryotic Cell Structures & Functions
Ch. 8 - Eukaryotic Cell Structures & Functions
Ch. 9 - Microscopes
Ch. 10 - Dynamics of Microbial Growth
Ch. 11 - Controlling Microbial Growth
Ch. 12 - Microbial Metabolism
Ch. 13 - Photosynthesis
Ch. 15 - DNA Replication
Ch. 16 - Central Dogma & Gene Regulation
Ch. 17 - Microbial Genetics
Ch. 18 - Biotechnology
Ch. 21 - Viruses, Viroids, & Prions
Ch. 22 - Innate Immunity
Ch. 23 - Adaptive Immunity
Ch. 24 - Principles of Disease
Symbiotic Relationships
The Human Microbiome
Characteristics of Infectious Disease
Stages of Infectious Disease Progression
Koch's Postulates
Molecular Koch's Postulates
Bacterial Pathogenesis
Introduction to Pathogenic Toxins
Exotoxins Cause Damage to the Host
Endotoxin Causes Damage to the Host
Exotoxins vs. Endotoxin Review
Immune Response Damage to the Host
Introduction to Avoiding Host Defense Mechanisms
1) Hide Within Host Cells
2) Avoiding Phagocytosis
3) Surviving Inside Phagocytic Cells
4) Avoiding Complement System
5) Avoiding Antibodies
Viruses Evade the Immune Response

Concept #1: Pathogens Avoid Encounter with Phagocytes

Practice: Why do some pathogens destroy the host organism’s C5a proteins?

Practice: What benefit do pathogenic bacteria obtain from secreting membrane-damaging toxins?

Concept #2: Pathogen Use Capsules & M Proteins to Avoid Opsonization

Practice: The C3b complement protein is incredibly important for opsonization of pathogenic material. How do some pathogens avoid opsonization by interfering with C3b?

Concept #3: Pathogens Use Fc Receptors to Prevent Opsonization

Practice: Certain pathogens have Fc receptors on their surface to avoid which immune responses to infection?

Practice: Why would some pathogens inhibit the functions of C3 convertase as a defense mechanism against the host’s immune cells?

Practice: Streptococcus pyogenes creates a C5a peptidase enzyme which breaks down the host’s C5a proteins. Breaking down the C5a proteins has what result?