Overview of DNA Replication Video Lessons

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Problem: If the gene for primase were mutated so that no functional primase was produced, what would be the effect on the two types of bacterial DNA replication?• Replication could proceed without a primase.• Replication would occur, but without proofreading mechanisms.• Replication would be unable to initiate.• Replication could occur only on the leading strand.• Replication would occur, but Okazaki fragments could not be connected on the lagging strand.

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Theta Replication: requires a primer

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Problem Details

If the gene for primase were mutated so that no functional primase was produced, what would be the effect on the two types of bacterial DNA replication?

• Replication could proceed without a primase.

• Replication would occur, but without proofreading mechanisms.

• Replication would be unable to initiate.

• Replication could occur only on the leading strand.

• Replication would occur, but Okazaki fragments could not be connected on the lagging strand.

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What scientific concept do you need to know in order to solve this problem?

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Based on our data, we think this problem is relevant for Professor Strickland's class at USOUTHAL.