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Problem: Several examples of antisense RNA regulating translation in bacterial cells have been discovered. If you wanted to design a construct to artificially control translation of a bacterial gene with antisense RNA, what type of sequences should the antisense RNA contain?A. A sequence complementary to the operator of an operon.B. A sequence complementary to a 5'–UTR.C. A sequence complementary to the Shine-Dalgarno site of the mRNA.D. Choices A and B are correct.E. Choices B and C are correct.

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Antisense RNA: single-strand DNA that hybridizes with mRNA, blocking translation

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Problem Details

Several examples of antisense RNA regulating translation in bacterial cells have been discovered. If you wanted to design a construct to artificially control translation of a bacterial gene with antisense RNA, what type of sequences should the antisense RNA contain?


A. A sequence complementary to the operator of an operon.

B. A sequence complementary to a 5'–UTR.

C. A sequence complementary to the Shine-Dalgarno site of the mRNA.

D. Choices A and B are correct.

E. Choices B and C are correct.

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