RNA Modification and Processing Video Lessons

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Problem: What would be the result of deleting the AAUAAA consensus sequence from a eukaryotic pre-mRNA? A) Transcription would stop before reaching the end of the gene-coding sequence, resulting in a shorter pre-mRNA transcript.B) The length of pre-mRNA sequence will not be affected, as the AAUAAA consensus sequence itself is not directly marking the cleavage site. C) Translation would continue past the end of the gene-coding sequence, resulting in a much longer amino acid sequence. D) The deletion itself will not affect the protein-coding region, but it may affect the polyadenylation at the 3 end, altering the mRNA stability.E) Translation would stop before reaching gene-coding sequence, resulting in a much o shorter amino acid sequence.

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Polyadenylation: mRNA modification at the 3' end; protects the mRNA from degradation

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Problem Details

What would be the result of deleting the AAUAAA consensus sequence from a eukaryotic pre-mRNA? 

A) Transcription would stop before reaching the end of the gene-coding sequence, resulting in a shorter pre-mRNA transcript.

B) The length of pre-mRNA sequence will not be affected, as the AAUAAA consensus sequence itself is not directly marking the cleavage site. 

C) Translation would continue past the end of the gene-coding sequence, resulting in a much longer amino acid sequence. 

D) The deletion itself will not affect the protein-coding region, but it may affect the polyadenylation at the 3 end, altering the mRNA stability.

E) Translation would stop before reaching gene-coding sequence, resulting in a much o shorter amino acid sequence.

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