Lac Operon Video Lessons

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Problem: In the lac operon, what are the likely effects on operon gene transcription of the mutations identified below?Mutation of consensus sequence in the lac promoterMutation of the repressor binding site on the operator sequenceMutation of the lac I gene affecting the allosteric site of the proteinMutation of the CAP binding site of the lac promoterMutation of the lac I gene affecting the DNA-binding site of the proteinA. Transcription is blocked.B. Transcription is constitutive.C. No effect on transcription

FREE Expert Solution

lac operon: synthesizes proteins for the metabolism of lactose (lac genes)

• when lactose and glucose are present, lac genes are not expressed

• when only lactose is present, lac genes are expressed


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Problem Details

In the lac operon, what are the likely effects on operon gene transcription of the mutations identified below?


Mutation of consensus sequence in the lac promoter

Mutation of the repressor binding site on the operator sequence

Mutation of the lac I gene affecting the allosteric site of the protein

Mutation of the CAP binding site of the lac promoter

Mutation of the lac I gene affecting the DNA-binding site of the protein


A. Transcription is blocked.

B. Transcription is constitutive.

C. No effect on transcription

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