The following sequence of DNA is part of the normal, wild-type gene: 5'–ATG CGG GTA GTT AGC CGA TAG–3'. An insertion occurs during DNA replication, causing an additional guanine to be inserted into the nucleotide strand after the guanine shown in bold. What effect will this have on the final protein?
A. The addition of the G will cause a single amino acid substitution in the codon in which it occurs.
B. The addition of the G will cause a frame shift, resulting in the loss of the normal stop codon and an abnormally long protein with an altered amino acid sequence.
C. The addition of the G will cause a frame shift, resulting in a premature stop codon and a truncated protein.
D. The addition of the G will cause a frame shift, so that the first amino acid after the mutation will change.
E. The addition of the G will not have an effect on the final protein
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