Problem: Which of the following is an example of a mutation?A. A frog is missing a leg because as an embryo it survived an attack by a predatorB. During transcription, RNA polymerase incorporates a U instead of an A (opposite a T in the DNA template)C. A phosphate group (-PO4) is added to an amino acid side chain in a polypeptide, which destroys its functionD. An A-T base pair in a gene is changed to a G-C base pairE. A methyl group (-CH3) is added to a cytosine base in DNA

Mutation: changes in the DNA sequence

Which of the following is an example of a mutation?

A. A frog is missing a leg because as an embryo it survived an attack by a predator

B. During transcription, RNA polymerase incorporates a U instead of an A (opposite a T in the DNA template)

C. A phosphate group (-PO₄) is added to an amino acid side chain in a polypeptide, which destroys its function

D. An A-T base pair in a gene is changed to a G-C base pair

E. A methyl group (-CH₃) is added to a cytosine base in DNA