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Problem: Refer to the figure below.This is a pedigree for a family in which several individuals develop a neurodegenerative disease late in life. If individual A has children with an unaffected woman, what is the probability that their first child will be affected? A) 0 percent B) 25 percent C) 33 percent D) 50 percent E) 100 percent

FREE Expert Solution

From the pedigree: inheritance is autosomal dominant → affected M/F individuals in every generation

Individual A:

• Father: A_

• Mother: aa

• For Individual A to have unaffected siblings → father must be Aa

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Problem Details

Refer to the figure below.

This is a pedigree for a family in which several individuals develop a neurodegenerative disease late in life. If individual A has children with an unaffected woman, what is the probability that their first child will be affected? 

A) 0 percent 

B) 25 percent 

C) 33 percent 

D) 50 percent 

E) 100 percent

Frequently Asked Questions

What scientific concept do you need to know in order to solve this problem?

Our tutors have indicated that to solve this problem you will need to apply the Pedigrees concept. You can view video lessons to learn Pedigrees. Or if you need more Pedigrees practice, you can also practice Pedigrees practice problems.

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Based on our data, we think this problem is relevant for Professor Dunham's class at UW-SEATTLE.