From the pedigree: inheritance is autosomal dominant → affected M/F individuals in every generation
• Father: A_
• Mother: aa
• For Individual A to have unaffected siblings → father must be Aa
Refer to the figure below.
This is a pedigree for a family in which several individuals develop a neurodegenerative disease late in life. If individual A has children with an unaffected woman, what is the probability that their first child will be affected?
A) 0 percent
B) 25 percent
C) 33 percent
D) 50 percent
E) 100 percent
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