Problem: The Henderson–Hasselbalch (H-H) equation is a clever rearrangement of the  Ka equilibrium expression that comes in very handy for certain pH calculations. The H-H equation can be used to calculate the buffer ratio ([base]/[acid]) required to prepare a buffer at a specific pH. It is possible that the buffer ratio required to prepare a pH 6.85 buffer could be used to study novel chemotherapy agents; however, the noble H-H equation can be used for more nefarious purposes.

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The Henderson–Hasselbalch (H-H) equation is a clever rearrangement of the  Ka equilibrium expression that comes in very handy for certain pH calculations. The H-H equation can be used to calculate the buffer ratio ([base]/[acid]) required to prepare a buffer at a specific pH. It is possible that the buffer ratio required to prepare a pH 6.85 buffer could be used to study novel chemotherapy agents; however, the noble H-H equation can be used for more nefarious purposes.

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Based on our data, we think this problem is relevant for Professor Dixon's class at UCF.