Problem: What is the ratio of HCO3- to H2CO3 in blood of pH 7.4?

FREE Expert Solution

We are asked for the ratio of HCO3- to H2CO3 in blood of pH 7.4. 

Since the solution is a buffer, we can use the Henderson-Hasselbalch Equation to calculate the ratio of [HCO3-]/[H2CO3] to have a pH of 7.4

pH = pKa + log conjugate baseweak acid


In the solution, identify the weak acid and the conjugate base. 

Recall from the Bronsted-Lowry definition that an acid is a proton (H+) donor and the base is a proton (H+) acceptor.

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What is the ratio of HCO3- to H2CO3 in blood of pH 7.4?

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What scientific concept do you need to know in order to solve this problem?

Our tutors have indicated that to solve this problem you will need to apply the Buffer concept. You can view video lessons to learn Buffer. Or if you need more Buffer practice, you can also practice Buffer practice problems.

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