Ch.14 - Chemical EquilibriumWorksheetSee all chapters
All Chapters
Ch.1 - Intro to General Chemistry
Ch.2 - Atoms & Elements
Ch.3 - Chemical Reactions
BONUS: Lab Techniques and Procedures
BONUS: Mathematical Operations and Functions
Ch.4 - Chemical Quantities & Aqueous Reactions
Ch.5 - Gases
Ch.6 - Thermochemistry
Ch.7 - Quantum Mechanics
Ch.8 - Periodic Properties of the Elements
Ch.9 - Bonding & Molecular Structure
Ch.10 - Molecular Shapes & Valence Bond Theory
Ch.11 - Liquids, Solids & Intermolecular Forces
Ch.12 - Solutions
Ch.13 - Chemical Kinetics
Ch.14 - Chemical Equilibrium
Ch.15 - Acid and Base Equilibrium
Ch.16 - Aqueous Equilibrium
Ch. 17 - Chemical Thermodynamics
Ch.18 - Electrochemistry
Ch.19 - Nuclear Chemistry
Ch.20 - Organic Chemistry
Ch.22 - Chemistry of the Nonmetals
Ch.23 - Transition Metals and Coordination Compounds

Solution: A chemist at a pharmaceutical company is measuring equilibrium constants for reactions in which drug candidate molecules bind to a protein involved in cancer. The drug molecules bind the protein in a

Problem

A chemist at a pharmaceutical company is measuring equilibrium constants for reactions in which drug candidate molecules bind to a protein involved in cancer. The drug molecules bind the protein in a 1:1 ratio to form a drug-protein complex. The protein concentration in aqueous solution at 25 oC is 1.72×10−6 M . Drug A is introduced into the protein solution at an initial concentration of 2.00 10-6 M. Drug B is introduced into a separate, identical protein solution at an initial concentration of 2.00 10-6 M. At equilibrium, the drug A-protein solution has an A-protein complex concentration of 1.00 10-6 M, and the drug B solution has a B-protein complex concentration of 1.40 10-6 M.

Calculate the Kc value for the A-protein binding reaction.