Problem: The structures of vitamins E and B6 are shown below.Predict which is more water soluble and which is more fat soluble.

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Analyze the structure of Vitamin B6 and Vitamin E and determine which is more soluble in water and fat.

Recall that water (H2O) is a polar molecule that exhibits hydrogen bonding, while fats/oil is a nonpolar molecule that exhibits dispersion forces. Using the concept of like dissolves like, we can determine which solvent is better for both compounds

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Problem Details

The structures of vitamins E and B6 are shown below.
Vitamin B6 is a six-membered nitrogen-containing ring attached to groups containing OH at three vertices. Vitamin E is a six-membered ring with carbon at all vertices. One vertex is attached to OH and another is attached to a second ring with one OH group and a long hydrocarbon chain.

Predict which is more water soluble and which is more fat soluble.