Codeine hydrochloride → salt
HC18H21NO3Cl → HC18H21NO3+ + Cl-
Equilibrium reaction: HC18H21NO3+(aq) + H2O(l) ⇌ C18H21NO3(aq) + H3O+(aq)
***HC18H21NO3+ conjugate acid of C18H21NO3
Step 1: Construct an ICE chart for the reaction.
Step 2: Write the Ka expression and calculate for Ka.
Solids and liquids are not included in the expression
Kb = 1.5849x10–6
Ka = 6.3096x10–9
Step 3: Calculate the equilibrium concentrations.
Codeine (C18H21NO3) is a narcotic pain reliever that forms a salt with HCl. What is the pH of 0.050 M codeine hydrochloride (pKb of codeine = 5.80)?
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