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Problem: Paclitaxel, C47H51NO14, is an anticancer compound that is difficult to make in the lab. One reported synthesis requires 11 steps, and the final yield of paclitaxel is only 6 %.Assuming all steps have equivalent yields, what is the average percent yield for each step in the synthesis?

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For a linear multi-step process, the overall percent yield is the product of the yields in each step. For example, if a process has two steps with 75% yield each, the overall yield is:

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Problem Details

Paclitaxel, C47H51NO14, is an anticancer compound that is difficult to make in the lab. One reported synthesis requires 11 steps, and the final yield of paclitaxel is only 6 %.

Assuming all steps have equivalent yields, what is the average percent yield for each step in the synthesis?

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Based on our data, we think this problem is relevant for Professor Dang's class at HCC.