The enzyme urease catalyzes the reaction of urea, (NH2CONH2), with water to produce carbon dioxide and ammonia. In water,
without the enzyme, the reaction proceeds with a first-order rate
constant of 4.15 x 10-5 s–1 at 100˚C. In the presence of the enzyme in water, the reaction proceeds with a rate constant of 3.4 x 104 s–1 at 21˚C. If the rate of the catalyzed reaction were the same at 100˚C as it is at 21˚C, what would be the difference in the activation energy between the catalyzed and uncatalyzed reactions? In actuality, what would you expect for the rate of the catalyzed reaction at 100˚C as compared to that at 21˚C?On the basis of your answers, what can you conclude about the difference in activation energies for the catalyzed and uncatalyzed reactions?