Enzyme Inhibitors: can be irreversible or reversible
How might you determine whether inhibition is reversible or irreversible? Drag the terms on the left to the appropriate blanks on the right to complete the sentences.
• if not
• nitrogen atoms
• if so
• heavy metals
Because irreversible inhibitors bind to the enzyme _______, you could analyze the enzyme molecule after adding the ______ to see if there was an increase of enzyme molecular weight or _________. You could test whether the inhibitor contains any _______, which often are irreversible inhibitors. You could test whether it is possible to separate the inhibitor from the inhibited enzyme (by dilution, for example) - _________, the inhibitor is irreversible.
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