DNA Topoisomerase: enzymes that participate in the overwinding or underwinding of DNA
During transcription elongation, what is the function of DNA topoisomerases?
A. identifying the region where termination will be taking place so that RNA polymerase can slow elongation before stopping
B. opening the DNA to form the transcription bubble for RNA polymerase to begin
C. coiling the DNA after RNA polymerase has passed by so that it is ready for the next round of transcription
D. removing positive DNA supercoils that are being produced by RNA polymerase
E. removing negative supercoiling so that the promoter region is available for sigma factor
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