Proteasomes: protein machines that break down large proteins to peptides
: 26S proteasome is composed of two 19S subunits and one 20S subunit
Choose the statements that correctly describe the structure and function of proteasomes.
A. The proteasome hydrolyzed the unfolded proteins to free amino acids, which are then recycled.
B. The 26S proteasome unit is composed of a 12S component and a 14S component.
C. One of the 19S regulatory particles cleaves ubiquitin from the protein.
D. Proteasomes would not be expected to use ATP to degrade small, unfolded peptides.
E. The proteolytic sites of the proteasome are located at the middle of the 20S core.
F. Proteasomes degrade proteins to small peptides.
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